Cutaneous angiofibroma is a term encompassing a range of skin lesions, including angiofibromas or "adenoma sebaceum" of tuberous sclerosis (TS) or multiple endocrine neoplasia type 1, fibrous papules of the face, pearly penile papules, and acral fibrokeratomas.

Fibrous papules of the face (also known as fibrous papules of the nose) are common, small, benign, skin-colored papules located on the nose or central face. Their onset is typically in middle age, and they are usually solitary or few in number. They are typically asymptomatic, although they may bleed with trauma. Their exact etiology is unknown, but some have suggested that fibrous papules represent nevi that no longer synthesize S-100 protein. Other studies involving electron microscopy suggest that they are derived from fibroblasts because premelanosomes and basal lamina are not seen.

There is no known predilection for a particular sex, ethnicity, or socioeconomic status.