Acral pseudolymphomatous angiokeratoma of children (APACHE) is a rarely reported, benign pseudolymphoma that presents predominantly in children and teenagers. The etiology is unknown, but it is classified as a pseudolymphoma due to its mixed B- and T-cell infiltrate.
APACHE is more common in females than males. Adult-onset cases have also been described. The clinical appearance of lesions varies. They most commonly appear as asymptomatic, unilateral, erythematous or violaceous angiomatous papules on an acral region, but they have been observed on the arm and leg. Papules are often clustered but may be solitary, linear, or coalescing into a plaque. There has been 1 reported case with accompanying nail plate dystrophy.
Without treatment, the lesions of APACHE will persist; however, treatment is not necessary given its benign nature.
Acral pseudolymphomatous angiokeratoma of children
Alerts and Notices
Important News & Links
Synopsis
Codes
ICD10CM:
D23.9 – Other benign neoplasm of skin, unspecified
SNOMEDCT:
402842008 – Acral pseudolymphomatous angiokeratoma of children (APACHE)
D23.9 – Other benign neoplasm of skin, unspecified
SNOMEDCT:
402842008 – Acral pseudolymphomatous angiokeratoma of children (APACHE)
Look For
Subscription Required
Diagnostic Pearls
Subscription Required
Differential Diagnosis & Pitfalls
To perform a comparison, select diagnoses from the classic differential
Subscription Required
Best Tests
Subscription Required
Management Pearls
Subscription Required
Therapy
Subscription Required
References
Subscription Required
Last Reviewed:06/19/2022
Last Updated:06/26/2022
Last Updated:06/26/2022
Acral pseudolymphomatous angiokeratoma of children