Eczema craquelé
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Synopsis

Xerosis is the predisposing factor to the development of eczema craquelé. The pathogenesis involves a decrease in the amount of lipids in the stratum corneum and a deficiency in the water-binding capacity of this layer. The condition is seen mostly in older adults; however, it can be associated with a number of environmental factors and/or disease states, such as low humidity, frequent bathing, harsh soaps, congenital and acquired ichthyoses, atopic dermatitis, hypothyroidism, Down syndrome, renal failure, malnutrition and malabsorptive states, HIV infection, lymphoma, liver disease, Sjögren syndrome, carcinomatosis, graft-versus-host disease, zinc deficiency, and certain drugs (in particular retinoids, diuretics, and protein kinase inhibitors).
Codes
L85.3 – Xerosis cutis
SNOMEDCT:
201077008 – Asteatotic eczema
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Last Updated:04/17/2025

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