Liver granuloma
Alerts and Notices
Important News & Links
Synopsis
Liver granulomas are most often caused by infection (tuberculosis, fungi), autoimmune disease (sarcoidosis, primary biliary cirrhosis), malignancy (Hodgkin lymphoma), or drug side effects (allopurinol). Sarcoidosis and tuberculosis are the most common causes of liver granulomas.
Symptoms and treatment of a liver granuloma vary with underlying etiology. A variety of proteins may be secreted by cells in granulomas, a few of which are characteristic of certain diseases (eg, elevated serum angiotensin-converting enzyme [ACE] suggests a diagnosis of active sarcoidosis). The presence of granulomas may only be identified through the workup of asymptomatic liver enzyme elevations or hepatomegaly on examination. In some patients, the cause of hepatic granulomas cannot be identified (10%-30%).
Codes
K75.3 – Granulomatous hepatitis, not elsewhere classified
SNOMEDCT:
714253009 – Hepatic granuloma
Look For
Subscription Required
Diagnostic Pearls
Subscription Required
Differential Diagnosis & Pitfalls
Subscription Required
Best Tests
Subscription Required
Management Pearls
Subscription Required
Therapy
Subscription Required
Drug Reaction Data
Subscription Required
References
Subscription Required
Last Updated:02/06/2018