Harlequin color change of newborn
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Synopsis
Most cases are idiopathic in healthy neonates. HCC has also been noted in the setting of prematurity, low birth weight, hypoxia, infusion of prostaglandin E1 (PGE1), and neonatal meningitis.
The transient color change lasts anywhere from 30 seconds to 20 minutes and recurs up to 12 times over a period of 24 hours. Of note, typical HCC occurs without changes in vital signs, pain, or other signs or symptoms. Hemiscrotal- and hemifacial-limited variants as well as a patchy erythema variant have been reported.
Codes
P29.89 – Other specified conditions originating in the perinatal period
SNOMEDCT:
276697006 – Harlequin change
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Last Updated:07/26/2020