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Peripheral giant cell granuloma - Oral Mucosal Lesion
Other Resources UpToDate PubMed

Peripheral giant cell granuloma - Oral Mucosal Lesion

Contributors: Belinda Tan MD, PhD, Carl Allen DDS, MSD, Sook-Bin Woo MS, DMD, MMSc
Other Resources UpToDate PubMed

Synopsis

The peripheral giant cell granuloma is a fairly common nodule on the gingiva caused by a proliferation of giant cells. It is likely caused by gingival and/or periodontal inflammation that results in differentiation of pluripotent cells into osteoclast-like or monocyte-like cells.

It tends to occur in older individuals in the fifth and sixth decades with a slight female predilection. The mandibular gingiva is more often involved than the maxillary. It is usually non-painful. Biting on it may induce bleeding since it is contains many blood vessels. It often occurs in the edentulous ridge. The lesion may lie in a cup-shaped depression in the underlying bone. Sometimes it may be difficult to tell if this is a purely extra-osseous process that has cupped the bone or whether it is an intra-osseous central giant cell granuloma that has broken through the bone and now has an extra-osseous or "peripheral" presentation. Unlike the central giant cell granulomas, these are not usually associated with hyperparathyroidism.

Codes

ICD10CM:
K13.4 – Granuloma and granuloma-like lesions of oral mucosa

SNOMEDCT:
89722009 – Giant cell peripheral granuloma

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Last Updated:11/13/2013
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Peripheral giant cell granuloma - Oral Mucosal Lesion
A medical illustration showing key findings of Peripheral giant cell granuloma : Gingival-alveolar mucosa, Purple color, Oral nodule
Clinical image of Peripheral giant cell granuloma - imageId=2506339. Click to open in gallery.  caption: 'A sessile reddish-purple, dusky nodule with overlying prominent telangiectasias on the gingiva.'
A sessile reddish-purple, dusky nodule with overlying prominent telangiectasias on the gingiva.
Copyright © 2024 VisualDx®. All rights reserved.