Nephrogenic systemic fibrosis
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Synopsis
NSF presents with thick, hard plaques on the extremities and trunk, leading to immobility and contracture of the joints. Systemic involvement (with fibrosis of skeletal muscle, myocardium, lungs, kidney, and testes) has been demonstrated in some patients.
The condition develops over days to weeks. About 5% of cases are fulminant and may result in death. The rapid new onset of fluctuating hypertension has been reported to precede skin changes.
Codes
L90.8 – Other atrophic disorders of skin
SNOMEDCT:
424114000 – Nephrogenic systemic fibrosis
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Last Updated:09/30/2019