Frontal fibrosing alopecia - Hair and Scalp
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Synopsis
Frontal fibrosing alopecia (FFA) is a form of scarring alopecia that presents as a progressive, symmetric band-like zone of hair loss along the anterior hairline. The eyebrows are often thinned or absent. It is considered a variant of lichen planopilaris in a patterned distribution. Women aged 55-65 years are most commonly affected, but younger women and men may be affected as well. A positive family history has been reported in 8% of cases.
There may be facial skin involvement (eg, perifollicular erythema or papules surrounding vellus hairs) in some cases, which may precede alopecia. Mucocutaneous lichen planus has occurred in up to 15% of cases.
There is a higher incidence of early menopause and history of hysterectomy without hormonal abnormalities on laboratory testing in affected women. Association with autoimmune conditions, such as vitiligo and hypothyroidism, has also been found. A recent study suggests that there is a possible link between sunscreen and moisturizer use and FFA, but the mechanism is unclear.
There may be facial skin involvement (eg, perifollicular erythema or papules surrounding vellus hairs) in some cases, which may precede alopecia. Mucocutaneous lichen planus has occurred in up to 15% of cases.
There is a higher incidence of early menopause and history of hysterectomy without hormonal abnormalities on laboratory testing in affected women. Association with autoimmune conditions, such as vitiligo and hypothyroidism, has also been found. A recent study suggests that there is a possible link between sunscreen and moisturizer use and FFA, but the mechanism is unclear.
Codes
ICD10CM:
L66.9 – Cicatricial alopecia, unspecified
SNOMEDCT:
717055000 – Frontal fibrosing alopecia
L66.9 – Cicatricial alopecia, unspecified
SNOMEDCT:
717055000 – Frontal fibrosing alopecia
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Last Reviewed:01/09/2022
Last Updated:11/01/2022
Last Updated:11/01/2022
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Frontal fibrosing alopecia - Hair and Scalp