Rare benign tumor consisting of a combination of mixed germ cells and sex cord stroma derivatives (Sertoli-like and granulosa-like cells), commonly arising in dysgenetic gonads. Occurs in males and phenotypic females with a Y chromosome. Tumors may produce excess testosterone or estrogen, causing findings such as abnormal genitalia, amenorrhea, virilization, and pelvic mass. Unilateral or bilateral. Most frequently diagnosed before the third decade. Lesion sizes vary from 1 mm up to 20 cm. May calcify. Associated with abnormal karyotype. Patients are at risk for developing a malignant germ cell tumor.
Gonadoblastoma
Alerts and Notices
Important News & Links
Synopsis
Codes
ICD10CM:
D39.10 – Neoplasm of uncertain behavior of unspecified ovary
D40.10 – Neoplasm of uncertain behavior of unspecified testis
SNOMEDCT:
74751003 – Gonadoblastoma
D39.10 – Neoplasm of uncertain behavior of unspecified ovary
D40.10 – Neoplasm of uncertain behavior of unspecified testis
SNOMEDCT:
74751003 – Gonadoblastoma
Differential Diagnosis & Pitfalls
To perform a comparison, select diagnoses from the classic differential
Subscription Required
Best Tests
Subscription Required
References
Subscription Required
Last Updated:02/18/2016
Gonadoblastoma