Progressive multifocal leukoencephalopathy
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Synopsis
Focal neurologic symptoms are typically subacute and evolve over weeks. Symptoms can include weakness, sensory loss, ataxia, vision changes, aphasia, cognitive decline, or behavioral changes. Seizures can also occur.
PML classically affects the subcortical white matter and U-fibers. Prognosis depends on severity of the underlying disease, although it is generally poor, and the disease is often fatal within months.
Codes
A81.2 – Progressive multifocal leukoencephalopathy
SNOMEDCT:
22255007 – Progressive multifocal leukoencephalopathy
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