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SynopsisCodesBest TestsDrug Reaction DataReferences
Minimal change disease
Other Resources UpToDate PubMed

Minimal change disease

Contributors: Catherine Moore MD
Other Resources UpToDate PubMed

Synopsis

The most common cause of nephrotic syndrome in children, this glomerular disease is characterized by normal glomerular appearance by light microscopy, no immune complexes on immunofluorescence, and diffuse podocyte foot process effacement on electron microscopy. Minimal change disease can also present in adulthood and is classically very responsive to steroids. The pathophysiology is not clear, but T-cell dysfunction is thought to be a significant factor.

Codes

ICD10CM:
N05.0 – Unspecified nephritic syndrome with minor glomerular abnormality

SNOMEDCT:
44785005 – Minimal change disease

Best Tests

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Drug Reaction Data

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References

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Last Updated:02/11/2016
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Minimal change disease
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A medical illustration showing key findings of Minimal change disease : Facial edema, Microscopic hematuria, Proteinuria, Weight gain, BP increased
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