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Drug-induced sticky palms
Other Resources UpToDate PubMed

Drug-induced sticky palms

Contributors: Vivian Wong MD, PhD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Sticky skin (acquired cutaneous adherence) is an adverse drug reaction associated with systemic retinoids, doxorubicin / ketoconazole combination therapy, and proton-pump inhibitors (lansoprazole and esomeprazole). The entire skin is affected, but stickiness is most exaggerated on the acral surfaces. Patients report a sticky sensation and a tendency for objects to adhere to the skin. The symptoms may be dose-dependent and respond to decreased dose or withdrawal of medication. While the pathomechanism is unknown, stratum corneum adherence to increased levels of glycoprotein in sweat has been postulated.

Codes

ICD10CM:
L27.1 – Localized skin eruption due to drugs and medicaments taken internally

SNOMEDCT:
102598000 – Clammy skin

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

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Therapy

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Drug Reaction Data

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References

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Last Updated:07/04/2016
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Drug-induced sticky palms
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A medical illustration showing key findings of Drug-induced sticky palms : Palms
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