Periorbital hyperpigmentation
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Synopsis
Many endogenous and exogenous factors can contribute to POH including genetics, postinflammatory hyperpigmentation (allergies, periorbital eczema), drug-related causes (vasodilatory medications, glaucoma medications such as latanoprost, hormonal therapy), procedures (blepharoplasty, rhinoplasty, chemical peels), and environmental / lifestyle changes (sun exposure, lack of sleep, stress, alcohol, caffeine, smoking).
The underlying pathogenetic mechanisms can be summarized as follows: increased melanocyte or melanophage density or increased melanin production; changes in vasculature; or mechanical changes in skin laxity, muscle, or tear trough that contribute to shadowing effect.
Codes
L81.4 – Other melanin hyperpigmentation
SNOMEDCT:
238703005 – Periorbital hypermelanosis
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Last Updated:10/04/2018