Congenital hemangioma
Alerts and Notices
Important News & Links
Synopsis
Congenital hemangiomas are benign pediatric vascular anomalies that can be divided into at least 4 categories: rapidly involuting (RICH), noninvoluting (NICH), partially involuting (PICH), and fetally involuting (FICH). Congenital hemangiomas arise in utero and are differentiated based upon their behavior. The RICH subtype begins regressing within the first few weeks of life, with complete regression by 6-14 months. The NICH subtype does not regress and may enlarge over time. The PICH subtype demonstrates a mix of rapid involution in some areas and noninvolution in others. This subtype exhibits the most rapid regression from birth to 12 months. The FICH subtype presents in utero and begins regression even before birth. FICH continues to regress after birth until it is fully involuted.
With all congenital hemangiomas, patients will present with a solitary lesion at birth. Some case reports show a slight male predominance. Patients with all subtypes of congenital hemangiomas are typically asymptomatic. However, there have been reports of pain in half of patients with the NICH subtype.
All subtypes are thought to be due to underlying activating mutation in the GNAQ gene. There have been no associations as of yet with any other conditions.
With all congenital hemangiomas, patients will present with a solitary lesion at birth. Some case reports show a slight male predominance. Patients with all subtypes of congenital hemangiomas are typically asymptomatic. However, there have been reports of pain in half of patients with the NICH subtype.
All subtypes are thought to be due to underlying activating mutation in the GNAQ gene. There have been no associations as of yet with any other conditions.
Codes
ICD10CM:
D18.00 – Hemangioma unspecified site
SNOMEDCT:
32361000119104 – Congenital hemangioma
D18.00 – Hemangioma unspecified site
SNOMEDCT:
32361000119104 – Congenital hemangioma
Look For
Subscription Required
Diagnostic Pearls
Subscription Required
Differential Diagnosis & Pitfalls
To perform a comparison, select diagnoses from the classic differential
Subscription Required
Best Tests
Subscription Required
Management Pearls
Subscription Required
Therapy
Subscription Required
References
Subscription Required
Last Reviewed:10/28/2018
Last Updated:09/25/2023
Last Updated:09/25/2023