Contents

SynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferences
Acquired brachial cutaneous dyschromatosis
Other Resources UpToDate PubMed

Acquired brachial cutaneous dyschromatosis

Contributors: Jacob Tribble BA, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Acquired brachial cutaneous dyschromatosis (ABCD) is a rare, asymptomatic skin disorder that presents with irregular, brown, hyperpigmented patches interspersed with hypopigmented macules on the dorsal aspect of the forearms.

There are two major hypotheses concerning the etiology of ABCD. The first suggests an association between hypertension (HTN) or antihypertensive agents (specifically angiotensin-converting enzyme inhibitors [ACEIs]). Studies have reported that nearly 65% of patients with ABCD have concurrent HTN, and of those 65%, the vast majority were utilizing ACEIs for treatment. The second proposes cumulative solar damage as the cause. Around 45% of patients diagnosed with ABCD have simultaneous poikiloderma of Civatte, lending support to the chronic sun damage hypothesis.

From the existing case reports, middle-to-older-aged adults with Fitzpatrick phototypes III and IV are most affected. Women vastly outnumber men, with postmenopausal women especially affected.

Codes

ICD10CM:
L81.9 – Disorder of pigmentation, unspecified

SNOMEDCT:
238698004 – Acquired hypermelanotic disorder

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

To perform a comparison, select diagnoses from the classic differential

Subscription Required

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

References

Subscription Required

Last Reviewed:10/14/2023
Last Updated:10/23/2023
Copyright © 2024 VisualDx®. All rights reserved.
Acquired brachial cutaneous dyschromatosis
Print  
A medical illustration showing key findings of Acquired brachial cutaneous dyschromatosis
Copyright © 2024 VisualDx®. All rights reserved.