Naso-orbital-ethmoid fractures are typically associated with severe maxillofacial trauma. Motor vehicle collisions are the most common cause. As the name implies, fracture to these structures potentially results in nasal deformity, obstruction, injury to the orbit, eyes, and supporting structures. The anterior skull base may also be involved.

These fractures typically require surgical intervention. Surgical repair may be highly complex, with the potential for long-time disfigurement from inadequately repaired injuries. Potential long-term complications include sinusitis, vision and smell impairment, and cerebral spinal fluid leaks.