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Transverse melanonychia - Nail and Distal Digit
Other Resources UpToDate PubMed

Transverse melanonychia - Nail and Distal Digit

Contributors: Sandrine Ménard BS, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Transverse melanonychia is a rarely reported phenomenon that is characterized by transverse brown or gray pigmentation of the nails. It is often drug-induced. Chemotherapeutic agents (including dasatinib, imatinib, cyclophosphamide, adriamycin, hydroxyurea, bleomycin, and etoposide) have been noted to induce transverse melanonychia. Other case reports have detailed electron beam therapy, quinacrine, infliximab, and zidovudine as inciting causes. Melanocyte activation is thought to be responsible pathomechanistically.

Codes

ICD10CM:
L60.8 – Other nail disorders

SNOMEDCT:
707197003 – Transverse melanonychia

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

To perform a comparison, select diagnoses from the classic differential

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Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

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References

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Last Reviewed:06/23/2024
Last Updated:06/30/2024
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Transverse melanonychia - Nail and Distal Digit
A medical illustration showing key findings of Transverse melanonychia
Copyright © 2024 VisualDx®. All rights reserved.