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Lichen sclerosus - Anogenital in
See also in: Overview,External and Internal Eye
Other Resources UpToDate PubMed

Lichen sclerosus - Anogenital in

See also in: Overview,External and Internal Eye
Contributors: Vivian Wong MD, PhD, Kudakwashe K. Maloney MD, MPhil, Belinda Tan MD, PhD, Susan Burgin MD, David Foster MD, Mary Gail Mercurio MD, Lynne Margesson MD
Other Resources UpToDate PubMed

Synopsis

Lichen sclerosus (LS) is the most common chronic vulvar condition. It is characterized by vulvar hypopigmentation and scarring with loss of normal architecture. Onset is typically at 35-45 years of age, but it can be seen in prepubertal children. Genetic and autoimmune factors are thought to contribute to the pathogenesis of LS.

The main symptom is pruritus, and at times, this can be incapacitating, interfering with daily activity and sleep. Dyspareunia and urinary retention may occur. It can also be asymptomatic, just with scarring and hypopigmentation.

Squamous cell carcinoma (SCC) can occur within LS genital lesions. There is a higher risk of SCC in untreated cases.

Codes

ICD10CM:
L90.0 – Lichen sclerosus et atrophicus

SNOMEDCT:
895454001 – Lichen sclerosus

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

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Best Tests

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Therapy

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Drug Reaction Data

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References

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Last Reviewed:08/12/2020
Last Updated:01/18/2022
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Patient Information for Lichen sclerosus - Anogenital in
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Lichen sclerosus - Anogenital in
See also in: Overview,External and Internal Eye
A medical illustration showing key findings of Lichen sclerosus : Eyelids, Glans of penis, Labia majora, Smooth plaque, White color, Inguinal region, Pruritus, Skin atrophy, Hardened skin
Clinical image of Lichen sclerosus - imageId=174921. Click to open in gallery.  caption: 'A shiny white plaque in the intergluteal fold.'
A shiny white plaque in the intergluteal fold.
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