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Large cell acanthoma
Other Resources UpToDate PubMed

Large cell acanthoma

Contributors: Fandi Xia MD, Chris G. Adigun MD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Large cell acanthoma is a relatively uncommon, benign neoplasm considered to be a subtype of solar lentigo or seborrheic keratosis. It typically presents as a scaly, tan macule or thin plaque on photodamaged skin, usually in elderly patients. Large cell acanthomas are characteristically solitary or few in number.

The etiology is unknown but thought to be related to extensive ultraviolet (UV) exposure. Analysis of clinical, histologic, and immunohistochemical properties suggests that the large cell acanthoma represents a reaction pattern evolving from a solar lentigo.

Codes

ICD10CM:
D23.9 – Other benign neoplasm of skin, unspecified

SNOMEDCT:
733894009 – Large cell acanthoma

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Last Reviewed:10/19/2020
Last Updated:11/15/2020
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Large cell acanthoma
A medical illustration showing key findings of Large cell acanthoma : Brown color, Pigmented plaque, Scaly plaque
Clinical image of Large cell acanthoma - imageId=1033472. Click to open in gallery.  caption: 'A close-up of a variegated pink and brown stuck-on, wrinkled plaque.'
A close-up of a variegated pink and brown stuck-on, wrinkled plaque.
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