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Drug-induced abdominal pain
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Drug-induced abdominal pain

Contributors: Michael W. Winter MD, Paritosh Prasad MD
Other Resources UpToDate PubMed

Synopsis

Abdominal pain may be associated with the use of a medication or other drug. Drug-induced abdominal pain is characterized by a sense of discomfort in the abdomen presenting soon after beginning a medication. Drugs that cause abdominal pain can also typically cause nausea, emesis, constipation, and diarrhea. In some cases, the pain may spontaneously self-resolve with continued use.

Persistent abdominal pain since starting a medication may be indicative of a more worrisome complication that warrants intervention, such as esophagitis, ulcer formation, colitis, perforation, cholecystitis, cholelithiasis, nephrolithiasis, pancreatitis, hepatitis, angioedema, chronic constipation, or anemia with chronic vascular compromise.

Many medications have been associated with abdominal pain (see Drug Reaction Data below), most commonly nonsteroidal anti-inflammatory drugs (NSAIDs).

Codes

ICD10CM:
R10.9 – Unspecified abdominal pain
T50.995A – Adverse effect of other drugs, medicaments and biological substances, initial encounter

SNOMEDCT:
21522001 – Abdominal pain
278993004 – Drug-induced

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Diagnostic Pearls

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Therapy

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Drug Reaction Data

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References

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Last Reviewed:01/01/2018
Last Updated:07/09/2020
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Drug-induced abdominal pain
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A medical illustration showing key findings of Drug-induced abdominal pain : Abdominal pain
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